1 Patch QELBY Hesperidin

These patches contain QELBY® powder





This is a somatid-based ceramic material that releases gentle warmth, microcurrents, negative electrons, and subtle UV and IR energy when it comes into contact with the skin. These signals interact with local tissues and promote soothing and comfort in the area where the patch is applied.

Hesperidin and Narirutin
These citrus flavonoids are extracted from tangerines grown on Jeju Island using a somatid-enhanced process. They are known for their ability to promote microcirculation, reduce oxidative stress, and help stabilize tissues in areas under tension.

6-Gingerol
Extracted from ginger using the same somatid technology. It is recognized for its natural warming properties and its role in supporting microcirculation and antioxidant pathways.

EZ-water complex gel
This gel contains the active compounds, reduces skin irritation, and allows the patch to stay in place for 7 to 10 days while gradually releasing energy and plant components.

The patch has successfully passed skin safety tests for human use conducted by the US FDA, with no adverse effects observed in over 100 participants, including children and the elderly. It is classified as a consumer wellness product.

How QELBY® Hesperidin Patches Work: The Science Behind Citrus Somatids, Gingerol, and EZ-Water Gel Technology

The QELBY® Hesperidin patch represents a new category of topical wellness technology. Rather than using synthetic chemicals or heating elements, this patch combines somatid-activated plant compounds with a natural EZ-water gel and QELBY® ceramic powder to provide continuous energy, promote circulation, and soothe tissues for up to ten days.

In this article, we analyze the science behind the key ingredients: QELBY® powder, hesperidin, narirutin, and 6-gingerol. These natural compounds work together through complementary mechanisms that promote circulation, antioxidant activity, microcurrent release, and cellular stability.

All ingredient information in this article is taken from JD Life Sciences technical documents, ingredient dossiers, and human skin safety test data from the FDA provided with the patch.

QELBY® Powder: The Somatid-Activated Energy Source

The core of the patch is QELBY® powder, created using JD Life Sciences Company's patented somatid technology. When placed on the body, the somatids in the powder naturally release:

• Negative electrons
• Subtle UV and IR reducing energy
• Microcurrents
• Gentle warmth

These signals penetrate through skin, glass, metal, and even wood. The patch uses this continuous low-intensity energy to influence microcirculation, soften hardened tissues, and promote local tissue recovery.

Users often report a sensation of warmth, softening of tense muscles, and increased comfort in the area where the patch is applied. This is a direct consequence of the somatids' activity interacting with sweat ducts, lymphatic pathways, and superficial blood vessels in the skin.

Hesperidin: Circulatory Support and Antioxidant Protection

Hesperidin is a flavonoid naturally found in citrus peels, but the hesperidin in this patch is not ordinary. It is extracted from tangerines grown on Jeju Island using JD Life Sciences Company's somatid-enhanced extraction method, which preserves its biological activity.

Circulatory Benefits

Hesperidin helps to:

• Strengthen capillary walls
• Reduce vascular permeability
• Promote good blood circulation
• Improve endothelial function

These actions are important for areas with stiffness, tension, or restricted microcirculation.

Antioxidant and Anti-inflammatory Effects

Hesperidin helps neutralize reactive oxygen species (ROS), thereby reducing oxidative stress that contributes to cellular aging and inflammation.

It also modulates COX-2, TNF-α, and IL-6 pathways, promoting relief in areas subject to chronic tension or irritation.

Neuro-calming Effects

Hesperidin interacts with GABA receptors, which can contribute to localized calming effects and general relaxation when used topically.

Narirutin: A Synergistic Citrus Compound for Tissue Stability

Narirutin, another citrus flavonoid extracted using somatid technology, acts synergistically with hesperidin to enhance the functional activity of the patch.

Potent Antioxidant Effects

Narirutin neutralizes free radicals, reduces lipid peroxidation, and promotes a balanced inflammatory response.

Circulatory Support

It contributes to:

• Improved blood flow
• Reduction of platelet aggregation
• Support for capillary elasticity
• Enhancement of vascular tone

These effects reinforce hesperidin's role in maintaining tissue health and blood circulation.

Cognitive and Cellular Support

Narirutin also protects neurons from oxidative damage and helps stabilize cellular energy pathways, including mitochondrial function.

6-Gingerol: Natural Heat Source and Microcirculation Stimulant

Ginger root contains numerous bioactive compounds, but 6-gingerol is its most recognized functional constituent. JD Life Sciences extracts it using a somatid-active process that preserves its warming and regenerative properties.

Anti-inflammatory and Antioxidant Benefits

6-gingerol helps regulate:

• NF-κB
• COX-2
• iNOS
• TNF-α
• IL-1β
• IL-6

All of these compounds (NF-κB, COX-2, iNOS, TNF-α, IL-1β, and IL-6) are cellular messengers or enzymes that help regulate inflammation. Natural compounds such as hesperidin, narirutin, and 6-gingerol are known to help modulate these pathways.

These pathways influence inflammatory responses in muscles, nerves, and connective tissues.

Microcirculation and Natural Warming

Gingerol helps improve blood circulation by reducing blood viscosity and promoting vasodilation. This is one reason why many users experience a sensation of warmth and increased comfort in the area where the patch is applied.

Cellular and Skin Benefits

6-gingerol promotes collagen synthesis, protects cells from oxidative stress, and encourages tissue repair.

The EZ-Water Complex Gel: Deep Penetration Without Irritation

The QELBY® Hesperidin patch uses a refined EZ-water complex gel that serves several functions:

• It transports somatid-activated compounds through the skin
• Reduces irritation
• It enhances absorption and moisture retention
• Stabilizes the hydrogel for long-term use
• Allows energy signals from QELBY® powder to effectively propagate into tissues

Since the gel is made from a natural silica-based adhesive, the patch can stay in place for 7 to 10 days while maintaining comfort and skin compatibility.

Qelby Hesperidin Patch -  INFORMATION FOR THERAPISTS

Manufacturing Process:
This hydrogel product is manufactured using patented somatid-based plant extraction technology (Korean Patent No. 10-1628995).
It is formulated by combining QELBY powder with active Somatide components extracted from tangerine (hesperidin, narirutin) and ginger (6-gingerol), as well as a bioactive complex gel based on 25% purified EZ water, mixed in a controlled weight ratio with natural silica-based skin adhesive ingredients.

Functional Ingredients and Mechanisms of Action

● QELBY Powder:
The somatid components in the powder naturally react upon contact with the skin, emitting heat, negative electrons, UV, and IR reducing energy.
These active energies penetrate deep into skin cells, as well as into materials such as glass, metal, and wood, to exert functional bioactive effects.

● Hesperidin (somatid extracted from tangerines grown on the volcanic island of Jeju)

Hesperidin - Functional Benefits

1) Vascular Strengthening and Improved Circulation

• Strengthens capillary walls, reduces vascular permeability, and improves blood circulation.
• Clinically proven to relieve varicose veins, hemorrhoids, and leg edema.
• Promotes vitamin C absorption, thereby strengthening endothelial function.

2) Antioxidant and Anti-inflammatory Effects

• Eliminates reactive oxygen species (ROS), helping to prevent cell damage and aging.
• Suppresses inflammatory mediators (COX-2, TNF-α, IL-6, etc.), contributing to the relief of chronic inflammatory disorders.
• Useful for the prevention of skin inflammations, allergic reactions, and diseases related to oxidative stress.

3) Neuroprotective and Anxiolytic Effects

• Activates GABA receptors in the brain, promoting relaxation and improved sleep quality.
• Protects neurons by preventing oxidative damage.
• Some studies suggest potential benefits in preventing Parkinson's and Alzheimer's diseases.

4) Cardiovascular and Metabolic Benefits

• Reduces LDL (bad cholesterol), increases HDL, and reduces triglycerides.
• Positively influences blood pressure regulation and insulin sensitivity, thereby helping to prevent hypertension and diabetes.

5) Antiviral Effects and Immune System Enhancement

• Demonstrated inhibitory effects on the protein binding of certain viruses such as influenza and COVID-19.
• Modulates immune responses and activates immune cells, maintaining immune balance.

6) Skin Protection and Anti-aging Effects

• Reduces skin damage caused by UV and inhibits collagen degradation.
• Promotes skin elasticity, helps reduce pigmentation, and contributes to brightening skin tone.

● Narirutin (somatidic extract from tangerines grown on the volcanic island of Jeju)

Developed using patented extraction technology applied to natural citrus grown in Jeju to preserve the high bioactivity and stability of functional compounds.

Narirutin – Functional Benefits

1) Antioxidant and Anti-inflammatory Effects

• Narirutin exhibits strong free radical scavenging activity, effectively neutralizing oxidative stress within cells.
• Its demonstrated actions include inhibiting oxidative stress (ROS), suppressing lipid peroxidation, and protecting against DNA damage.
• It suppresses the expression of inflammatory mediators (TNF-α, IL-1β, IL-6, NO, etc.), thereby helping to alleviate chronic inflammation, arthritis, allergies, and dermatitis.

2) Vascular Strengthening and Circulation Improvement

• Helps prevent damage to vascular endothelial cells and maintain capillary elasticity.
• It is believed to increase blood flow, inhibit platelet aggregation, and stabilize blood pressure.
• When combined with hesperidin, it produces a synergistic effect in improving microcirculation.

3) Neuroprotection and Cognitive Function Enhancement

• Narirutin suppresses inflammation and oxidative stress in the brain, thereby preventing neuronal cell death and improving memory and cognitive functions.
• By promoting dopamine synthesis and enhancing mitochondrial function, it exhibits potential preventative effects against Parkinson's disease, dementia, and stress-related neurological disorders.

4) Immune Regulation and Antiviral Effects

• It modulates the activity of immune cells (macrophages and T-cells), suppressing excessive immune responses while enhancing immune defenses.
• It demonstrates inhibitory activity on viral protein replication enzymes, with research indicating potential efficacy against RNA viruses such as influenza and COVID-19.

5) Skin Regeneration and Whitening Effects

• Inhibits UV-induced skin inflammation, pigmentation, and collagen degradation.
• It suppresses melanin, enhances skin hydration and elasticity, and accelerates wound healing, making it a valuable natural ingredient for cosmetics and transdermal patches.

6) Metabolic Regulation and Anti-Obesity Effects

• Regulates lipid metabolism in liver cells, inhibits fat synthesis, and improves blood glucose control.
• Through AMPK pathway activation, it enhances energy metabolism, suppresses fat accumulation, and contributes to the prevention of metabolic disorders.

● 6-Gingerol (Somatid extract from natural ginger cultivated in Korea)

6-Gingerol – Functional Benefits

1) Anti-inflammatory and Antioxidant Effects

• 6-Gingerol inhibits intracellular signaling pathways such as NF-κB, COX-2, and iNOS, thereby blocking the production of inflammatory mediators (TNF-α, IL-1β, IL-6, etc.).
• It scavenges Reactive Oxygen Species (ROS) and increases glutathione (GSH) levels, thereby delaying cellular aging.
• It thus helps alleviate chronic inflammation, arthritis, gastritis, dermatitis, and vascular inflammation.

2) Neuroprotective Effects and Cognitive Function Enhancement

• 6-Gingerol suppresses oxidative stress in brain cells and protects dopaminergic neurons, giving it potential in preventing Parkinson's disease, dementia, and post-stroke neuronal damage.
• It inhibits acetylcholinesterase (AChE), thereby helping to improve memory and concentration.
• It also enhances cerebral blood flow, helping to prevent cognitive decline.

3) Anti-cancer Effects and Promotion of Cell Regeneration

• Demonstrated ability to induce cell cycle arrest (G1/S phase) and apoptosis in cancer cells.
• It has been shown to inhibit the proliferation of colon, breast, prostate, and lung cancer cells.
• Simultaneously mitigates oxidative stress in normal cells, thereby promoting cell regeneration and tissue repair.

4) Blood Circulation Improvement and Antiplatelet Effects

• Promotes vasodilation, inhibits platelet aggregation, and improves blood circulation.
• Reduces blood viscosity and improves microcirculation, effectively relieving cold extremities, numbness, and circulatory disorders.

5) Analgesic and Antipyretic Effects

• Regulates TRPV1 receptors, responsible for pain perception, helping to relieve muscle pain, neuralgia, menstrual cramps, and inflammatory pain.
• Improves peripheral blood circulation and promotes natural body temperature regulation, with a slight antipyretic effect.

6) Antibacterial, Antiviral, and Immune-Boosting Effects

• 6-Gingerol inhibits key enzymes and proteins of various bacteria and viruses, thereby helping to prevent respiratory infections, enteritis, and dermatitis.
• It activates macrophages and NK (natural killer) cells, thereby promoting immune system balance.

7) Skin Health, Blood Circulation, and Metabolic Benefits

• Increases blood flow to the skin, producing a warming and self-heating effect.
• It promotes collagen synthesis and suppresses melanin production, thereby improving skin elasticity and whitening.
• It regulates lipid metabolism and improves insulin sensitivity, thereby helping to prevent metabolic syndrome.

The QELBY Hesperidin Patch is manufactured using JD Life Science Company, Ltd.'s proprietary Somatid core technology, which integrates QELBY powder with a natural complex gel containing hesperidin and narirutin (bioactive compounds extracted from citrus fruits) and 6-gingerol (derived from natural ginger extract).

As an innovative product, the Somatid citrus-derived hesperidin and narirutin gel, combined with ginger-derived 6-gingerol Somatid, demonstrates superior performance when used as a cosmetic additive: it enhances skin penetration, prevents skin irritation and damage, and offers anti-inflammatory, hemostatic, analgesic, and cell regenerative effects.
It is a natural and non-toxic formulation that provides rapid absorption and functional efficacy comparable to pharmaceutical products, without side effects.

The substances used (ginger extract, citrus extract, QELBY powder, hesperidin, and narirutin) are all registered ingredients in the INCI (International Nomenclature of Cosmetic Ingredients) in Europe and the United States.

What can you expect to feel after applying the patch?

After applying the patch, you may experience an itchy sensation in the treated area for two to three days, depending on the condition and location on the body. You may also feel a slight electrical sensation, similar to a pinprick. This is a 100% positive reaction to the process and not a side effect.

Additionally, patients with severe inflammation or nerve damage in the intervertebral discs or skin may experience local pain for three days to a week during treatment. This can also be due to the negative electrons, microcurrent, infrared rays, and oxygen released by the patch, which cause immediate dilation of sweat channels and peripheral blood vessels and penetrate deeply into the affected area. This process of removing waste and toxins from the blood and cells through sweat gland channels and the skin can cause itching, a slight electrical discharge, and pain. Depending on individuals and their symptoms, these symptoms will gradually disappear, ultimately leading to fundamental improvement.